Ferulic acid
CAS No. | 1135-24-6 | Cat. No. | BCP21789 |
Name | Ferulic acid | ||
Synonyms | 4-Hydroxy-3-methoxycinnamic acid;Coniferic acid;NSC 2821; NSC2821; NSC-2821; | ||
Formula | C10H10O4 | M. Wt | 194.19 |
Description | erulic Acid is a fibroblast growth factor receptor 1 (FGFR1) inhibitor that has antioxidant, anti-inflammatory and anticancer properties. Ferulic acid increased monoamine neurotransmitter levels in the brain regions that are relative to mood disorders: the hippocampus and frontal cortex. The increased tend to serotonin and norepinephrine was also found in the hypothalamus after higher dose of ferulic acid treatment. Monoamine oxidase A (MAO-A) activity was inhibited in the frontal cortex and hippocampus when treatment with 40 and 80 mg/kg ferulic acid; while MAO-B activity did not change significantly. Ferulic acid provides neuroprotective effects against a middle cerebral artery occlusion (MCAO)-induced cerebral ischemia. | ||
Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
Targets | FGFR |
Structure
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