Escitalopram oxalate

  • Chemical Properties
CAS No. 219861-08-2 Cat. No. BCP05686
Name Escitalopram oxalate
Synonyms (S)-(+)Citalopram oxalate;Cipralex;Lexapro;
Formula C22H23FN2O5 M. Wt 414.43
  • Biological Activity
Description Escitalopram, the S-enantiomer of citalopram, belongs to a class of antidepressant agents known as selective serotonin-reuptake inhibitors (SSRIs). Escitalopram may be used to treat major depressive disorder (MDD) and generalized anxiety disorder (GAD). Escitalopram has no significant affinity for adrenergic (alpha1, alpha2, beta), cholinergic, GABA, dopaminergic, histaminergic, serotonergic (5HT1A, 5HT1B, 5HT2), or benzodiazepine receptors; antagonism of such receptors has been hypothesized to be associated with various anticholinergic, sedative, and cardiovascular effects for other psychotropic drugs. The chronic administration of escitalopram is found to downregulate brain norepinephrine receptors, as has been observed with other drugs effective in the treatment of major depressive disorder. Escitalopram does not inhibit monoamine oxidase.
Pathways Neuro Signaling Pathway 
Targets SSRI 

Structure

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