Bupivacaine

  • Chemical Properties
CAS No. 2180-92-9 Cat. No. BCP21825
Name Bupivacaine
Synonyms Marcaine; AH-250; HSDB 7790; SKY 0402; SKY0402; AH 250; AH250; HSDB7790; HSDB-7790; SKY-0402; Win-11318; Win11318;
Formula C18H28N2O M. Wt 288.43
  • Biological Activity
Description Bupivacaine, is a medication used to freeze tissue in a specific area. It is used by injecting it into the area, around a nerve that supplies the area, or into the spinal canal's epidural space. It is available mixed with a small amount of epinephrine to make it last longer. It typically begins working within 15 minutes and lasts for 2 to 8 hours. Bupivacaine binds to the intracellular portion of voltage-gated sodium channels and blocks sodium influx into nerve cells, which prevents depolarization. Without depolarization, no initiation or conduction of a pain signal can occur.
Pathways PI3K/Akt/mTOR MAPK Pathway 
Targets RSK 

Structure

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