Asenapine maleate
| CAS No. | 85650-56-2 | Cat. No. | BCP05157 |
| Name | Asenapine maleate | ||
| Synonyms | Org 5222; Org5222; Org-5222; HSDB 8061; HSDB-8061; HSDB8061; | ||
| Formula | C17H16ClNO.C4H4O4 | M. Wt | 401.84 |
| Description | Asenapine maleate is a 5-HT (1A, 1B, 2A, 2B, 2C, 5A, 6, 7) and D2 angonist with Ki values of 0.03-4.0 nM, 1.3nM,respectively, and an antipsychotic. Asenapine, also known as Org 5222 and HSDB 8061, is an atypical antipsychotic developed for the treatment of schizophrenia and acute mania associated with bipolar disorder. Preliminary data indicate that it has minimal anticholinergic and cardiovascular side effects, as well as minimal weight gain. FDA approved thisderug in August 2009. | ||
| Pathways | Neuro Signaling Pathway GPCR/G Protein | ||
| Targets | 5 HT Receptor/Serotonin Receptor Adrenergic Receptor | ||
Structure
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