Darapladib

  • Chemical Properties
CAS No. 356057-34-6 Cat. No. BCP04908
Name Darapladib
Synonyms SB-480848; SB480848; SB 480848;
Formula C36H38F4N4O2S M. Wt 666.77
  • Biological Activity
Description Darapladib, is a novel inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2), an enzyme that may link lipid metabolism with inflammation, leading to the increased stability of atherosclerotic plaques present in the major arteries. Darapladib is being studied as a possible add-on treatment for atherosclerosis.
Pathways Protease/Metabolic Enzyme 
Targets Phospholipase 

Structure

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