Nafamostat mesylate
| CAS No. | 82956-11-4 | Cat. No. | BCP04841 |
| Name | Nafamostat mesylate | ||
| Synonyms | Nafamostat mesilate; FUT-175; FUT 175; FUT175; | ||
| Formula | C21H25N5O8S2 | M. Wt | 539.58 |
| Description | Nafamostat, also known as FUT-175, is a serine protease inhibitor and an anticoagulant. Nafamostat promotes endothelium-dependent vasorelaxation via the Akt-eNOS dependent pathway. Nafamostat Attenuates Ischemia-Reperfusion-Induced Renal Injury. Nafamostat Attenuates Ischemia-Reperfusion-Induced Renal Injury. Nafamostat protects against acute cerebral ischemia via blood-brain barrier protection. Nafamostat Inhibits TNF-α-Induced Vascular Endothelial Cell Dysfunction by Inhibiting Reactive Oxygen Species Production. | ||
| Pathways | Protease/Metabolic Enzyme | ||
| Targets | Serine Protease | ||
Structure
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