Alvimopan

  • Chemical Properties
CAS No. 156053-89-3 Cat. No. BCP04794
Name Alvimopan
Synonyms ADL 8-2698;Entereg;HSDB 7704; HSDB7704; HSDB-7704; LY 246736; LY246736; LY-246736; ADL 82698;
Formula C25H32N2O4 M. Wt 424.53
  • Biological Activity
Description Upon administration, Alvimopan(ADL 8-2698; Entereg; LY 246736) binds to mu-opioid receptors in the gut, thereby reversing opiod-related disturbances in gut motility. Alvimopan is approximately three to nine times more potent than naloxone.A synthetic trans-3,4-dimethyl-4-(3-hydroxyphenyl) piperidine with peripherally selective opioid mu receptor antagonist activity.
Pathways Neuro Signaling Pathway Hormone Pathay GPCR/G Protein 
Targets Opioid Receptor 

Structure

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