Dexmedetomidine HCl

CAS No.	145108-58-3	Cat. No.	BCP04768
Name	Dexmedetomidine HCl
Synonyms	Dexmedetomidine hydrochloride;
Formula	C13H16N2.HCl	M. Wt	236.74

Description	Dexmedetomidine, acting at alpha(2A) adrenoceptors, must be present during the encoding process to decrease discrete cue fear memory; however, its ability to suppress contextual memory is likely the result of blocking the consolidation process. Dexmedetomidine had no analgesic effects in alpha(2A)-adrenoceptor KO mice. Dexmedetomidine was effective in blocking these sympathomimetic actions of cocaine even in all 7 subjects who were homozygous for the Del322-325 polymorphism in the alpha2C AR, a loss-of-function mutation that is highly enriched in blacks.
Pathways	Neuro Signaling Pathway GPCR/G Protein
Targets	Adrenergic Receptor

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