LY2874455
CAS No. | 1254473-64-7 | Cat. No. | BCP04756 |
Name | LY2874455 | ||
Synonyms | LY 2874455;LY-2874455; | ||
Formula | C21H19Cl2N5O2 | M. Wt | 444.31 |
Description | LY2874455 exhibits a potent activity against FGF/FGFR-mediated signaling in several cancer cell lines and shows an excellent broad spectrum of antitumor activity in several tumor xenograft models representing the major FGF/FGFR relevant tumor histologies including lung, gastric, and bladder cancers and multiple myeloma, and with a well-defined pharmacokinetic/pharmacodynamic relationship. | ||
Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
Targets | FGFR |
Structure
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