Copanlisib

  • Chemical Properties
CAS No. 1032568-63-0 Cat. No. BCP04754
Name Copanlisib
Synonyms BAY80-6946; BAY-80-6946; BAY806946; BAY-806946; BAY 806946;
Formula C23H28N8O4 M. Wt 480.52
  • Biological Activity
Description Copanlisib also known as BAY 80-6946, is a potent phosphoinositide 3-kinase (PI3K) inhibitor. Copanlisib inhibits the activation of the PI3K signaling pathway, which may result in inhibition of tumor cell growth and survival in susceptible tumor cell populations. Activation of the PI3K signaling pathway is frequently associated with tumorigenesis and dysregulated PI3K signaling may contribute to tumor resistance to a variety of antineoplastic agents. Copanlisib was approved for the treatment of adult patients experiencing relapsed follicular lymphoma who have received at least two prior systemic therapies.
Pathways PI3K/Akt/mTOR 
Targets PI3K 

Structure

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