A-803467
| CAS No. | 944261-79-4 | Cat. No. | BCP04519 |
| Name | A-803467 | ||
| Synonyms | A803467; A 803467; | ||
| Formula | C19H16ClNO4 | M. Wt | 357.79 |
| Description | A 803467 is a selective Nav1.8 sodium channel blocker and analgesic. A 803467 blocks Nav1.8 with an IC50 of 8 nM and is over 100-fold more selective vs. human Nav1.2, 1.3, 1.5 and 1.7. A 803467 dose-dependently reduces behavioral responses in a variety of neuropathic and inflammatory pain models. | ||
| Pathways | Ion Channel/Membrane Transporter | ||
| Targets | Sodium Channel | ||
Structure
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