Ambroxol
| CAS No. | 18683-91-5 | Cat. No. | BCP04489 |
| Name | Ambroxol | ||
| Synonyms | NA-872;NA 872;NA872; | ||
| Formula | C13H18Br2N2O | M. Wt | 378.1 |
| Description | Ambroxol inhibits Na+ channels in sensory neurons. The potency for tonic block of TTX-r channels is relatively high. Ambroxol affects the Na+ current kinetics of TTX-r and TTX-s channels differently. In CNaIIA cells, the compound behaves like a charged local anesthetic: the block is dependent on stimulus number and increases with higher frequencies in a train of depolarizing stimuli. In CNaIIA cells, ambroxol inhibits inactivated channels 5.5-fold more potently than resting channels. The corresponding factor for TTX-r channels is only 3.3.Ambroxol inhibits the release of histamine, leukotrienes and cytokines from human leukocytes and mast cells. | ||
| Pathways | Others Pathway | ||
| Targets | Others | ||
Structure
Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.
For product details of different batches, please contact our Customer
- Service & Tech Support:orders@biochempartner.com
- Website:www.biochempartner.com
Products are for research use only and not for human use. We do not sell to patients.