Compound 401

  • Chemical Properties
CAS No. 168425-64-7 Cat. No. BCP04303
Name Compound 401
Synonyms 2-(Morpholin-4-yl)pyrimido[2,1-a]isoquinolin-4-one;
Formula C16H15N3O2 M. Wt 281.31
  • Biological Activity
Description Compound 401 exhibits much reduced or no activity against 43 other commonly studied kinases, including PI 3-K, ATM, and ATR. Compound 401 has been shown to induce apoptosis and inhibit FRAP-dependent growth in TSC1-/- murine embryo fibroblasts.
Pathways Cell Cycle/DNA Damage PI3K/Akt/mTOR 
Targets DNA PK 

Structure

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