Verteporfin
| CAS No. | 129497-78-5 | Cat. No. | BCP04238 |
| Name | Verteporfin | ||
| Synonyms | CL 318952;CL318952;CL-318952;BPD-MA; | ||
| Formula | C41H42N4O8 | M. Wt | 718.79 |
| Description | Verteporfin is a potent second-generation photosensitizing agent derived from porphyrin. It is used as a photosensitizer for photodynamic therapy to eliminate abnormal blood vessels in the eye that are associated with conditions such as macular degeneration. Verteporfin also suppresses the formation of autophagosome via targeting p62, which binds both polyubiquitinated proteins destined for degradation and LC3 on autophagosomal membranes. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
| Targets | VDA | ||
Structure
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