Vorozole

  • Chemical Properties
CAS No. 129731-10-8 Cat. No. BCP04202
Name Vorozole
Synonyms R-83842;R 83842;R83842;
Formula C16H13ClN6 M. Wt 324.77
  • Biological Activity
Description Vorozole is an imidazole based competitive inhibitor of the aromatase enzyme. It underwent clinical testing for evaluation for use as an antineoplastic agent; however it was withdrawn from testing when no difference was detected in the duration of median survival as compared to the progestational agent megestrol acetate and research instead focused on the other third generation aromatase inhibitors anastrozole, letrozole and exemestane. The enzyme is selective.
Pathways Hormone Pathay 
Targets Aromatase 

Structure

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