Desonide

CAS No.	638-94-8	Cat. No.	BCP04201
Name	Desonide
Synonyms	Locapred;Topifug;Tridesilon;D-2083;D 2083;D2083;
Formula	C24H32O6	M. Wt	416.51

Description	Desonide is a low-potency topical corticosteroid that has been used for decades in the treatment of steroid-responsive dermatoses . Desonide induced significant colorimetric improvement compared with placebo. A good to excellent response was achieved in 30% for desonide, and 6% for placebo. Decreased pigmentation in the desonide-treated axillae was associated with recovery of disruption at the basal membrane. Desonide showed depigmenting properties in women with axillary hyperpigmentation . Given the favorable safety profile of all other desonide preparations and their utility as a low potency corticosteroid, desonide foam promises to be a useful addition to the armamentarium, when other desonide vehicles might be less acceptable.
Pathways	GPCR/G Protein
Targets	Glucocorticoid Receptor

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