野百合碱

化学数据

CAS号	315-22-0	货号	BCP04181
中文名	野百合碱
英文名	Monocrotaline
中文别名
英文别名	A 6080;A-6080;A6080;
分子式	C16H24NO6	分子量	325.36

用途

生物活性	Monocrotaline is a natural ligand that exhibits dose-dependent cytotoxicity as a pyrrolizidine alkaloid and toxic plant constituent; the alkaloid causes pulmonary artery hypertension, right ventricular hypertrophy, and pathological changes in the pulmonary vasculature. However, it also has therapeutic potential against hepatocellular carcinoma. It acts against p53, HGF and TREM1 proteins, which play a threatening role in causing hepatocellular carcinoma. It is a novel scaffold for liver cancer with superior efficacy and lesser side effects.

生物活性

Monocrotaline is a natural ligand that exhibits dose-dependent cytotoxicity as a pyrrolizidine alkaloid and toxic plant constituent; the alkaloid causes pulmonary artery hypertension, right ventricular hypertrophy, and pathological changes in the pulmonary vasculature. However, it also has therapeutic potential against hepatocellular carcinoma. It acts against p53, HGF and TREM1 proteins, which play a threatening role in causing hepatocellular carcinoma. It is a novel scaffold for liver cancer with superior efficacy and lesser side effects.

结构式

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