Clocortolone pivalate

  • Chemical Properties
CAS No. 34097-16-0 Cat. No. BCP22647
Name Clocortolone pivalate
Synonyms Clocortolone 21-pivalate;
Formula C27H36ClFO5 M. Wt 495.02
  • Biological Activity
Description Clocortolone Pivalate is a glucocorticoid receptor agonist with metabolic, anti-inflammatory, and immunosuppressive activity. Clocortolone pivalate exerts its effect by interacting with specific intracellular receptors and subsequently binds to DNA to modify gene expression. This results in an induction of the synthesis of certain anti-inflammatory proteins while inhibiting the synthesis of certain inflammatory mediators. Consequently, an overall reduction in chronic inflammation and autoimmune reactions are accomplished.
Pathways GPCR/G Protein 
Targets Glucocorticoid Receptor 

Structure

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