Fluorometholone
| CAS No. | 426-13-1 | Cat. No. | BCP04127 |
| Name | Fluorometholone | ||
| Synonyms | NSC33001;NSC 33001;NSC-33001;U-8614; | ||
| Formula | C22H29FO4 | M. Wt | 376.46 |
| Description | Fluorometholone is a synthetic glucocorticoid that binds to glucocorticoid receptors (IC50 = 1.5 nM; Kd = 2.8 nM in a radioligand binding assay). Fluorometholone (0.01%) decreases survival of cultured corneal epithelial cells and inhibits their migration in a scratch assay following 12 hours of treatment. Formulations containing fluorometholone have been used for the treatment of eye inflammation. | ||
| Pathways | GPCR/G Protein | ||
| Targets | Glucocorticoid Receptor | ||
Structure
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