Dovitinib lactate monohydrate
  • Chemical Properties
CAS No. 915769-50-5 Cat. No. BCP04112
Name Dovitinib lactate monohydrate
Synonyms TKI258; TKI-258; TKI 258; CHIR258; CHIR-258; CHIR 258;Dovitinib lactate;
Formula C21H21FN6O.C3H6O3.H2O M. Wt 500.52
  • Biological Activity
Description Dovitinib (TKI258, CHIR258) is a novel multi-target inhibitor for Flt3, c-Kit, FGFR1/3, VEGFR1/2/3 with IC50 of 1 nM, 2 nM, 8 nM/9 nM and 10 nM/13 nM/8 nM, respectively.
Pathways Angiogenesis/Protein Tyrosine Kinase 
Targets PDGFR VEGFR c Kit FLT3 FGFR 

Structure

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