AZD-6126
| CAS No. | 219923-05-4 | Cat. No. | BCP04084 |
| Name | AZD-6126 | ||
| Synonyms | ANG453;AZD 6126;AZD6126;ANG 453;ANG-453; | ||
| Formula | C20H24NO8P | M. Wt | 437.38 |
| Description | AZD6126, also known as ANG-453, a water-soluble phosphate prodrug of N-acetylcolchinol with potential antiangiogenesis and antineoplastic activities. AZD-6126 is an angiogenesis inhibitor and tubulin inhibitor potentially for the treatment of solid tumours. AZD6126 is converted in vivo into N-acetylcolchinol. N-acetylcolchinol binds to and destabilizes the tubulin cytoskeleton of endothelial cells in tumor blood vessels, which may result in tumor endothelial cel apoptosis, the selective occlusion of tumor blood vessels, cessation of tumor blood flow, and tumor necrosis. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
| Targets | VDA | ||
Structure
Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.
For product details of different batches, please contact our Customer
- Service & Tech Support:orders@biochempartner.com
- Website:www.biochempartner.com
Products are for research use only and not for human use. We do not sell to patients.