Ranolazine dihydrochloride

  • Chemical Properties
CAS No. 95635-56-6 Cat. No. BCP22680
Name Ranolazine dihydrochloride
Synonyms Ranolazine 2HCl;RS 43285; RS-43285; RS43285; CVT-303; CVT 303; CVT303;
Formula C24H35Cl2N3O4 M. Wt 500.46
  • Biological Activity
Description Ranolazine is an anti-ischemic compound, which inhibits late sodium current that results in a reduction of Na+ dependent Ca2+ overload. Studies indicate that ATP production is shifted towards glucose oxidation by Ranolazine. This is due to the fact that more oxygen is required to phosphorylate the same amount of ATP during fatty acid oxidation than carbohydrate oxidation. These studies indicate that Ranolazine also inhibits oxygen consumption and ketogenesis by fatty acids in liver cells.
Pathways Ion Channel/Membrane Transporter 
Targets Calcium Channel Sodium Channel 

Structure

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