塞卡替尼
| CAS号 | 379231-04-6 | 货号 | BCP01733 |
| 中文名 | 塞卡替尼 | ||
| 英文名 | Saracatinib | ||
| 中文别名 | |||
| 英文别名 | AZD0530; AZD-0530;AZD 0530; | ||
| 分子式 | C27H32ClN5O5 | 分子量 | 542.03 |
| 生物活性 | Saracatinib, also known as AZD0530, is an orally available dual-specific inhibitor of Src and Abl with anti-invasive and anti-tumor activities. Src and Abl are protein tyrosine kinases that are overexpressed in chronic myeloid leukemia cells. Saracatinib binds to and inhibits these tyrosine kinases and their effects on cell motility, cell migration, adhesion, invasion, proliferation, differentiation, and survival. | ||
| 上下游产品 | 893428-72-3（塞卡替尼富马酸盐） | ||
| 信号通路 | Angiogenesis/Protein Tyrosine Kinase | ||
| 靶 点 | Src/Bcr Abl | ||
结构式
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