Pioditazone hydrochloride
| CAS No. | 112529-15-4 | Cat. No. | BCP22942 |
| Name | Pioditazone hydrochloride | ||
| Synonyms | Pioglitazone HCl; Actos; U-72107A; U 72107A;U72107A;AD 4833; AD-4833; AD4833; | ||
| Formula | C19H21ClN2O3S | M. Wt | 392.9 |
| Description | Pioglitazone Hydrochloride is the hydrochloride salt of an orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic activity. Pioglitazone activates peroxisome proliferator-activated receptor gamma (PPAR-gamma), a ligand-activated transcription factor, thereby inducing cell differentiation and inhibiting cell growth and angiogenesis. This agent also modulates the transcription of insulin-responsive genes, inhibits macrophage and monocyte activation, and stimulates adipocyte differentiation. | ||
| Pathways | Cell Cycle/DNA Damage | ||
| Targets | PPAR | ||
Structure
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