盐酸匹格列酮
| CAS号 | 112529-15-4 | 货号 | BCP22942 |
| 中文名 | 盐酸匹格列酮 | ||
| 英文名 | Pioditazone hydrochloride | ||
| 中文别名 | 安可妥; | ||
| 英文别名 | Pioglitazone HCl; Actos; U-72107A; U 72107A;U72107A;AD 4833; AD-4833; AD4833; | ||
| 分子式 | C19H21ClN2O3S | 分子量 | 392.9 |
| 生物活性 | Pioglitazone Hydrochloride is the hydrochloride salt of an orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic activity. Pioglitazone activates peroxisome proliferator-activated receptor gamma (PPAR-gamma), a ligand-activated transcription factor, thereby inducing cell differentiation and inhibiting cell growth and angiogenesis. This agent also modulates the transcription of insulin-responsive genes, inhibits macrophage and monocyte activation, and stimulates adipocyte differentiation. | ||
| 信号通路 | Cell Cycle/DNA Damage | ||
| 靶 点 | PPAR | ||
结构式
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