Tazarotene

  • Chemical Properties
CAS No. 118292-40-3 Cat. No. BCP22966
Name Tazarotene
Synonyms AGN190168, AGN-190168; AGN 190168;
Formula C21H21NO2S M. Wt 351.46
  • Biological Activity
Description Tazarotene is a third-generation prescription topical retinoid. Tazarotene is a retinoid prodrug which is converted to its active form, the cognate carboxylic acid of tazarotene, by rapid deesterification in animals and humans. Tazarotenic acid binds to all three members of the retinoic acid receptor (RAR) family: RARα, RARβ, and RARγ but shows relative selectivity for RARβ, and RARγ and may modify gene expression.
Pathways Protease/Metabolic Enzyme 
Targets RAR/RXR 

Structure

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