拉索昔芬
| CAS号 | 180916-16-9 | 货号 | BCP03626 |
| 中文名 | 拉索昔芬 | ||
| 英文名 | Lasofoxifene | ||
| 中文别名 | |||
| 英文别名 | CP 336156; CP336156; CP-336156; CP 336,156; CP336,156; CP-33,6156; | ||
| 分子式 | C28H31NO2 | 分子量 | 413.55 |
| 生物活性 | Lasofoxifene, also known as CP 336156, is a non-steroidal selective estrogen receptor modulator (SERM) for the prevention and treatment of osteoporosis and for the treatment of vaginal atrophy. In September 2005, Pfizer received a non-approvable letter from the U.S. Food and Drug Administration regarding lasofoxifene (trade name Oporia), a selective estrogen receptor modulator for the prevention of osteoporosis. Lasofoxifene was approved in the EU under the brand name Fablyn by the EMEA in March 2009. Lasofoxifene is a desmethyl dihydro analog of nafoxidine. | ||
| 上下游产品 | 190791-29-8（酒石酸拉索昔芬） | ||
| 信号通路 | Hormone Pathay | ||
| 靶 点 | Estrogen Receptor | ||
结构式
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