Etravirine
| CAS No. | 269055-15-4 | Cat. No. | BCP03562 |
| Name | Etravirine | ||
| Synonyms | TMC-125;TMC 125;TMC125; | ||
| Formula | C20H15BrN6O | M. Wt | 435.28 |
| Description | Etravirine (TMC125), is highly active against wild-type HIV-1 with EC50 of 1.4 nM to 4.8 nM and shows some activity against HIV-2 with EC50 of 3.5 μM. TMC125 also inhibits a series of HIV-1 group M subtypes and circulating recombinant forms and a group O virus. | ||
| Pathways | Microbiology/Virology | ||
| Targets | Reverse Transcriptase HIV | ||
Structure
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