A66
| CAS No. | 1166227-08-2 | Cat. No. | BCP03474 |
| Name | A66 | ||
| Synonyms | A 66;A-66; | ||
| Formula | C17H23N5O2S2 | M. Wt | 393.53 |
| Description | A66 is a potent and highly selective p110α inhibitor with IC50 of 32 nM in a cell-free assay, >100 fold selectivity for p110α over other class-I PI3K isoforms. A66 blocks phosphoinositide 3-kinase signalling and tumour growth in certain cell types. | ||
| Pathways | PI3K/Akt/mTOR | ||
| Targets | PI3K | ||
Structure
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