PNU282987hcl
| CAS No. | 123464-89-1 | Cat. No. | BCP03492 |
| Name | PNU282987hcl | ||
| Synonyms | PNU 282987;PNU-282987; | ||
| Formula | C14H18Cl2N2O | M. Wt | 301.21 |
| Description | This novel agonist of the α7 nAChR has been utilized in multiple model brain investigations of this receptor. Utilizing rat hippocampal slices PNU-282,987 has been reported to evoke whole-cell currents. PNU-282,987 is hypothesized to modulate or enhance GABAergic hippocampal neurotransmission. Additionally, in mouse cerebellum, ethanol-induced ataxia was attenuated in a dose-dependant fashion with administration of PNU-282,987. PNU-282,987 has also been used in various studies to investigate the effects of the compound on hippocampal theta oscillation. | ||
| Pathways | Neuro Signaling Pathway | ||
| Targets | nAChR | ||
Structure
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