Abiraterone Acetate
CAS No. | 154229-18-2 | Cat. No. | BCP02949 |
Name | Abiraterone Acetate | ||
Synonyms | (3β)-17-(3-Pyridinyl)androsta-5,16-dien-3-ol Acetate (Ester);CB 7630;CB-7630;CB7630; | ||
Formula | C26H33NO2 | M. Wt | 391.55 |
Description | Abiraterone Acetate is an orally active acetate sester form of the steroidal compound abiraterone with antiandrogen activity. Abiraterone inhibits the enzymatic activity of steroid 17alpha-monooxygenase (17alpha-hydrolase/C17,20 lyase complex), a member of the cytochrome p450 family that catalyzes the 17alpha-hydroxylation of steroid intermediates involved in testosterone synthesis. Administration of this agent may suppress testosterone production by both the testes and the adrenals to castrate-range levels. | ||
Pathways | Protease/Metabolic Enzyme | ||
Targets | Cytochrome P450 |
Structure
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