SKF 89976A HCl
| CAS No. | 85375-15-1 | Cat. No. | BCP02921 |
| Name | SKF 89976A HCl | ||
| Synonyms | SKF-89976A;SKF89976A; | ||
| Formula | C22H25NO2.HCl | M. Wt | 371.9 |
| Description | SKF 89976A is a GABA transporter type 1 inhibitor with IC50 of 0.13, 550, 944 and 7210 μM for hGABA T-1, rGABa T-2, hGABA T-3 and hBGT-1 respectively. SKF-89976A is selective for GABA T-1. This compound inhibits transport current competitively (Ki = 7 μM) and transmitter-gated current non-competitively. | ||
| Pathways | Ion Channel/Membrane Transporter Neuro Signaling Pathway | ||
| Targets | GABA Receptor | ||
Structure
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