Etoposide
| CAS No. | 33419-42-0 | Cat. No. | BCP02859 |
| Name | Etoposide | ||
| Synonyms | Etopophos; | ||
| Formula | C29H32O13 | M. Wt | 588.56 |
| Description | Etoposide inhibits the growth of murine angiosarcoma cell line (ISOS-1) in a 5 days-period with IC50 of 0.25 μg/mL. Cell growth of normal murine microvascular endothelial cells (mECs) is less sensitive to Etoposide with IC50 of 10 μg/mL). Etoposide treated for 6 hr inhibits colonies of tetraploid variant of the human leukemic lymphoblast line CCRF-CEM with IC50 of 0.6 μM . Etoposide administrated as a single agent is found to been ineffective in many xenografts growth, such as Heterotransplanted Hepatoblastoma NMHB1, and NMHB 2 . Etoposide administrated as a single agent is found to been ineffective in many xenografts growth, such as Heterotransplanted Hepatoblastoma NMHB1, and NMHB 2 , human neuroblastoma xenograft. | ||
| Pathways | Cell Cycle/DNA Damage | ||
| Targets | Topoisomerase | ||
Structure
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