WZ3146
| CAS No. | 1214265-56-1 | Cat. No. | BCP02838 |
| Name | WZ3146 | ||
| Synonyms | WZ 3146;WZ-3146; | ||
| Formula | C24H25ClN6O2 | M. Wt | 464.95 |
| Description | WZ3146 significantly suppresses the growth of EGFR mutation containing cell lines with IC50 of 3 nM in EGFR Del E746_A750 containing HCC827 cells, 15 nM in EGFR Del E746_A750 containing PC9 cells, 29 nM in EGFR L858R/T790M containing H1975 cells and 3 nM in EGFR Del E746_A750/T790M containing PC9 GR cells. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase Jak/Stat Pathway | ||
| Targets | EGFR | ||
Structure
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