Bedaquiline
| CAS No. | 843663-66-1 | Cat. No. | BCP02829 |
| Name | Bedaquiline | ||
| Synonyms | R207910;R 207910;R-207910;TMC 207;TMC-207;TMC207; | ||
| Formula | C32H31BrN2O2 | M. Wt | 555.51 |
| Description | Bedaquiline, also known as TMC207 and R207910, is a diarylquinoline anti-tuberculosis drug. Bedaquiline blocks the proton pump for ATP synthase of mycobacteria. ATP production is required for cellular energy production and its loss leads to cell death, even in dormant or nonreplicating mycobacteria.It is the first member of a new class of drugs called the diarylquinolines. Bedaquiline is bactericidal. | ||
| Related Products | 845533-86-0（Bedaquiline fumarate） | ||
| Pathways | Microbiology/Virology | ||
| Targets | Antibiotic | ||
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Primary Clofazimine and Bedaquiline Resistance among Isolates from Patients with Multidrug-Resistant Tuberculosis
Publications Citing of Biochempartner's Bedaquiline(CAS:843663-66-1) |
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In Vitro Activity of Clofazimine against Nontuberculous Mycobacteria Isolated in Beijing, China
Publications Citing of Biochempartner's Bedaquiline(CAS:843663-66-1) |
Structure
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