贝达喹啉
| CAS号 | 843663-66-1 | 货号 | BCP02829 |
| 中文名 | 贝达喹啉 | ||
| 英文名 | Bedaquiline | ||
| 中文别名 | |||
| 英文别名 | R207910;R 207910;R-207910;TMC 207;TMC-207;TMC207; | ||
| 分子式 | C32H31BrN2O2 | 分子量 | 555.51 |
| 生物活性 | Bedaquiline, also known as TMC207 and R207910, is a diarylquinoline anti-tuberculosis drug. Bedaquiline blocks the proton pump for ATP synthase of mycobacteria. ATP production is required for cellular energy production and its loss leads to cell death, even in dormant or nonreplicating mycobacteria.It is the first member of a new class of drugs called the diarylquinolines. Bedaquiline is bactericidal. | ||
| 上下游产品 | 845533-86-0（贝达喹啉富马酸盐） | ||
| 信号通路 | Microbiology/Virology | ||
| 靶 点 | Antibiotic | ||
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Primary Clofazimine and Bedaquiline Resistance among Isolates from Patients with Multidrug-Resistant Tuberculosis
购于瀚香生物(Biochempartner)的贝达喹啉(CAS:843663-66-1)被引用 |
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In Vitro Activity of Clofazimine against Nontuberculous Mycobacteria Isolated in Beijing, China
购于瀚香生物(Biochempartner)的贝达喹啉(CAS:843663-66-1)被引用 |
结构式
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