RS504393
| CAS No. | 300816-15-3 | Cat. No. | BCP02713 |
| Name | RS504393 | ||
| Synonyms | RS 504393;RS-504393; | ||
| Formula | C25H27N3O3 | M. Wt | 417.5 |
| Description | Extremely selective CCR2 chemokine receptor antagonist (IC50 values are 98 nM and > 100 μM for inhibition of human recombinant CCR2b and CCR1 receptors respectively). Inhibits MCP-1 chemotaxis (IC50 = 330 nM) and ischemia-reperfusion injury in kidneys. | ||
| Pathways | GPCR/G Protein | ||
| Targets | CCR | ||
Structure
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