Enzastaurin
| CAS No. | 170364-57-5 | Cat. No. | BCP02703 |
| Name | Enzastaurin | ||
| Synonyms | LY317615;LY-317615;LY 317615; DB-102; DB 102; DB102; | ||
| Formula | C32H29N5O2 | M. Wt | 515.62 |
| Description | Enzastaurin is a synthetic macrocyclic bisindolemaleimide with potential antineoplastic activity. Binding to the ATP-binding site, enzastaurin selectively inhibits protein kinase C beta, an enzyme involved in the induction of vascular endothelial growth factor (VEGF)-stimulated neo-angiogenesis. This agent may decrease tumor blood supply and so tumor burden. | ||
| Pathways | TGF beta/Smad Epigenetics | ||
| Targets | PKC | ||
Structure
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