Fasudil hydrochloride
CAS No. | 105628-07-7 | Cat. No. | BCP26351 |
Name | Fasudil hydrochloride | ||
Synonyms | HA-1077;HA 1077;HA1077; AT 877; AT877; AT-877; Fasudil HCl; | ||
Formula | C14H17N3O2S.HCl | M. Wt | 327.83 |
Description | Fasudil, also known as HA-1077, is a potent Rho-kinase inhibitor and vasodilator. Since it was discovered, it has been used for the treatment of cerebral vasospasm, which is often due to subarachnoid hemorrhage, as well as to improve the cognitive decline seen in stroke victims. It has been found to be effective for the treatment of pulmonary hypertension. It was demonstrated in February 2009 that fasudil could also be used to enhance memory and improve the prognosis of Alzheimers patients. It is approved for use in Japan and China. | ||
Pathways | Cell Cycle/DNA Damage Others Pathway TGF beta/Smad GPCR/G Protein Wnt/Stem Cell | ||
Targets | Autophagy ROCK PKA |
Suppression of glioblastoma by a drug cocktail reprogramming tumor cells into neuronal like cells
Publications Citing of Biochempartner's Fasudil hydrochloride(CAS:105628-07-7) |
Structure
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