盐酸法舒地尔
| CAS号 | 105628-07-7 | 货号 | BCP26351 |
| 中文名 | 盐酸法舒地尔 | ||
| 英文名 | Fasudil hydrochloride | ||
| 中文别名 | |||
| 英文别名 | HA-1077;HA 1077;HA1077; AT 877; AT877; AT-877; Fasudil HCl; | ||
| 分子式 | C14H17N3O2S.HCl | 分子量 | 327.83 |
| 生物活性 | Fasudil, also known as HA-1077, is a potent Rho-kinase inhibitor and vasodilator. Since it was discovered, it has been used for the treatment of cerebral vasospasm, which is often due to subarachnoid hemorrhage, as well as to improve the cognitive decline seen in stroke victims. It has been found to be effective for the treatment of pulmonary hypertension. It was demonstrated in February 2009 that fasudil could also be used to enhance memory and improve the prognosis of Alzheimers patients. It is approved for use in Japan and China. | ||
| 信号通路 | Cell Cycle/DNA Damage Others Pathway TGF beta/Smad GPCR/G Protein Wnt/Stem Cell | ||
| 靶 点 | Autophagy ROCK PKA | ||
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Suppression of glioblastoma by a drug cocktail reprogramming tumor cells into neuronal like cells
购于瀚香生物(Biochempartner)的盐酸法舒地尔(CAS:105628-07-7)被引用 |
结构式
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