Verucerfont
| CAS No. | 885220-61-1 | Cat. No. | BCP26371 |
| Name | Verucerfont | ||
| Synonyms | GSK561679A;GSK-561679;GSK 561679;GSK561679; SK-561,679; NBI77860; NBI-77860; NBI 77860; | ||
| Formula | C22H26N6O2 | M. Wt | 406.49 |
| Description | Verucerfont, also known as GSK561679 and NBI77860, is a CRF-1 antagonist. Verucerfont blocks the CRH-1 receptor, and so reduces ACTH release following chronic stress. It is under investigation as a potential treatment for alcoholism, as chronic stress is often a factor in both development of alcoholism and relapse in recovering alcoholics. It has shown promising results in animal studies but has not been tested in humans. | ||
| Pathways | GPCR/G Protein | ||
| Targets | CRFR | ||
Structure
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