Verucerfont
| CAS号 | 885220-61-1 | 货号 | BCP26371 |
| 中文名 | Verucerfont | ||
| 英文名 | Verucerfont | ||
| 中文别名 | |||
| 英文别名 | GSK561679A;GSK-561679;GSK 561679;GSK561679; SK-561,679; NBI77860; NBI-77860; NBI 77860; | ||
| 分子式 | C22H26N6O2 | 分子量 | 406.49 |
| 生物活性 | Verucerfont, also known as GSK561679 and NBI77860, is a CRF-1 antagonist. Verucerfont blocks the CRH-1 receptor, and so reduces ACTH release following chronic stress. It is under investigation as a potential treatment for alcoholism, as chronic stress is often a factor in both development of alcoholism and relapse in recovering alcoholics. It has shown promising results in animal studies but has not been tested in humans. | ||
| 信号通路 | GPCR/G Protein | ||
| 靶 点 | CRFR | ||
结构式
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