CP154526
CAS No. | 157286-86-7 | Cat. No. | BCP26372 |
Name | CP154526 | ||
Synonyms | CP-154526;CP 154526;CP 154,526; CP-154,526; CP154,526; | ||
Formula | C23H32N4 | M. Wt | 364.53 |
Description | CP 154,526 is a selective, non-peptide CRF1 receptor antagonist (Ki values are 2.7 and > 10000 nM for CRF1 and CRF2 receptors respectively). CP 154,526 blocks CRF-induced adenylate cyclase activation (Ki = 3.7 nM) and attenuates activation of the HPA axis by CRF. | ||
Pathways | GPCR/G Protein | ||
Targets | CRFR |
Structure
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