Clascoterone

  • Chemical Properties
CAS No. 19608-29-8 Cat. No. BCP02565
Name Clascoterone
Synonyms CB-03-01;CB 03-01; CB03-01; Cortexolone 17alpha-propionate;Cortexolone 17α-propionate;17 alpha-propionate;17α-propionate; Cortexolone 17 alpha-propionate;
Formula C24H34O5 M. Wt 402.52
  • Biological Activity
Description Clascoterone, also known as CB-03-01 and cortexolone 17alpha-propionate, is a topical and peripherally selective and potent androgen antagonist for topical treatment of acne vulgaris. CB-03-01 1% cream seems to fit with the profile of an ideal antiandrogen for topical use. CB-03-01 is clinically more effective than comparator. Acne vulgaris is a disorder of the pilosebaceous unit in which the androgens contribute to its onset and persistence. The use of antiandrogens is therefore potentially effective.
Pathways Hormone Pathay 
Targets Androgen Receptor  

Structure

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