Calcipotriol
| CAS No. | 112828-00-9;112965-21-6 | Cat. No. | BCP26578 |
| Name | Calcipotriol | ||
| Synonyms | Calcipotriene; calcipotriol; Calciptriol; Calcitrene; CCRIS 7700; Daivonex; Dovonex; MC 903; PRI 2201; Psorcutan; Sorilux; | ||
| Formula | C27H40O3 | M. Wt | 412.6 |
| Description | Calcipotriol, a synthetic derivative of calcitriol or Vitamin D, is used in the treatment of psoriasis and marketed under the trade name Dovonex. It has comparable affinity with calcitriol (Vit. D) for the Vitamin D receptor (VDR), while being less than 1% as active as the calcitriol in regulating calcium metabolism. Chronic plaque psoriasis is the chief medical use of calcipotriol. It has also been used successfully in the treatment of alopecia areata. | ||
| Pathways | Others Pathway | ||
| Targets | Vitamin D Related | ||
Structure
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