Cediranib
CAS No. | 288383-20-0 | Cat. No. | BCP01378 |
Name | Cediranib | ||
Synonyms | AZD2171;Recentin;AZD 2171;AZD-2171; | ||
Formula | C25H27FN4O3 | M. Wt | 450.51 |
Description | Cediranib, also known as AZD-2171, is a potent and selective VEGF inhibitor with antineoplastic activities. Competing with adenosine triphosphate, cediranib binds to and inhibits all three vascular endothelial growth factor receptor (VEGF-1,-2,-3) tyrosine kinases, thereby blocking VEGF-signaling, angiogenesis, and tumor cell growth. | ||
Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
Targets | PDGFR VEGFR |
Structure
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