Idarubicin hydrochloride

  • Chemical Properties
CAS No. 57852-57-0 Cat. No. BCP01381
Name Idarubicin hydrochloride
Synonyms IMI30; IMI-30; IMI 30; NSC256439; NSC-256439; NSC 256439;4-Demethoxydaunorubicin hydrochloride;Zavedos;4-demethoxydaunorubicin;Idarubicin HCl;
Formula C26H27NO9.HCl M. Wt 533.95
  • Biological Activity
Description Idarubicin is a semisynthetic 4-demethoxy analogue of the antineoplastic anthracycline antibiotic daunorubicin. Idarubicin intercalates into DNA and interferes with the activity of topoisomerase II, thereby inhibiting DNA replication, RNA transcription and protein synthesis. Due to its high lipophilicity, idarubicin penetrates cell membranes more efficiently than other anthracycline antibiotic compounds.
Related Products 58957-92-9(Idarubicin)
Pathways Cell Cycle/DNA Damage 
Targets Topoisomerase 

Structure

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