Rivaroxaban
| CAS No. | 366789-02-8 | Cat. No. | BCP00165 |
| Name | Rivaroxaban | ||
| Synonyms | BAY59-7939; BAY 59-7939; BAY-59-7939;Xarelto; | ||
| Formula | C19H18ClN3O5S | M. Wt | 435.88 |
| Description | Rivaroxaban also inhibits prothrombinase activity with IC50 of 2.1 nM. Rivaroxaban also shows a similar affinity to purified human and rabbit FXa (IC50 0.7 nM and 0.8 nM, respectively), but a lesser potency against purified rat FXa (IC50 3.4 nM). Endogenous human and rabbit FXa in plasma is inhibited to a similar extent by Rivaroxaban (IC50 21 nM and 21 nM, respectively), while 14-fold higher concentrations are required in rat plasma (IC50 290 nM). | ||
| Pathways | Protease/Metabolic Enzyme | ||
| Targets | Factor Xa | ||
Structure
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