Posaconazole
| CAS No. | 171228-49-2 | Cat. No. | BCP01102 |
| Name | Posaconazole | ||
| Synonyms | Noxafil; SCH-56592; Schering 56592; Sch 56592; Schering-56592; | ||
| Formula | C37H42F2N8O4 | M. Wt | 700.78 |
| Description | Posaconazole is a triazole antifungal drug. Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity. Posaconazole strongly inhibits 14-alpha demethylase, a cytochrome P450-dependent enzyme. Inhibition of 14-alpha-demethylase prevents the conversion of lanosterol to ergosterol, an important component of the fungal cell wall. Compared to other azole antifungals, posaconazole is a significantly more potent inhibitor of sterol 14-alpha demethylase. | ||
| Pathways | Microbiology/Virology | ||
| Targets | Antifungal | ||
Structure
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