GLP-1 (7-37) Acetate

  • Chemical Properties
CAS No. 106612-94-6 Cat. No. BCP01989
Name GLP-1 (7-37) Acetate
Synonyms Insulinotropin;GLP-1 (7-37) peptide; Glucagon like Peptide-1 (7-37) Acetate;7-37-Glucagon-like peptide I (human);Insulinotropin (human);Peptide GLP-1 (human glucose-lowering peptide-1);
Formula C151H228N40O47 M. Wt 3355.67
  • Biological Activity
Description GLP-1 (7-37) is a potent stimulator of insulin secretion at concentrations as low as 5 X 10(-11) M (3- to 10-fold increases over basal). GLP-I(1-37) had no effect on insulin secretion even at concentrations as high as 5 X 10(-7) M. The earlier demonstration of specific liberation of GLP-I(7-37) in the intestine and pancreas, and the magnitude of the insulinotropic effect at such low concentrations, suggest that GLP-I(7-37) participates in the physiological regulation of insulin secretion.
Pathways GPCR/G Protein 
Targets Glucagon Receptor 

Structure

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