GLP-1 (7-37) Acetate
CAS No. | 106612-94-6 | Cat. No. | BCP01989 |
Name | GLP-1 (7-37) Acetate | ||
Synonyms | Insulinotropin;GLP-1 (7-37) peptide; Glucagon like Peptide-1 (7-37) Acetate;7-37-Glucagon-like peptide I (human);Insulinotropin (human);Peptide GLP-1 (human glucose-lowering peptide-1); | ||
Formula | C151H228N40O47 | M. Wt | 3355.67 |
Description | GLP-1 (7-37) is a potent stimulator of insulin secretion at concentrations as low as 5 X 10(-11) M (3- to 10-fold increases over basal). GLP-I(1-37) had no effect on insulin secretion even at concentrations as high as 5 X 10(-7) M. The earlier demonstration of specific liberation of GLP-I(7-37) in the intestine and pancreas, and the magnitude of the insulinotropic effect at such low concentrations, suggest that GLP-I(7-37) participates in the physiological regulation of insulin secretion. | ||
Pathways | GPCR/G Protein | ||
Targets | Glucagon Receptor |
Structure
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